A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)
Phase 1/2
15
about 2.2 years
18+
2 sites in IL, NY
Why this study is shown
What this study is about
This trial is testing a treatment called LP-118 with other medicines like ponatinib, vincristine, and dexamethasone in people whose leukemia has returned after treatment or hasn't responded to previous treatments. The goal is to find out if LP-118 can be used safely along with these other medications.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Dexamethasone
- 2.Take LP-118
- 3.Take Methotrexate
- +2 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
dexamethasone, methotrexate, ponatinib, vincristine
injection, ocular, oral (Oral Tablet)
Secondary: Complete Clinical Remission (CR) with Measurable Residual Disease (MRD), Overall Survival, Progression-Free Survival
Oncology