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Study details
Enrolling now

A Study of AZD0486 for B-Cell Non-Hodgkin Lymphoma

AstraZeneca
NCT IDNCT04594642ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

317

Study length

about 7.1 years

Ages

18–130

Locations

10 sites in FL, KY, NC +6

Why this study is shown

Actively enrollingPHASE1

What this study is about

This trial is testing the safety and how well AZD0486 works in people with B-cell non-Hodgkin lymphoma. AZD0486 is a type of drug given through an IV infusion.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive AZD0486 IV

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

infusion

Endpoints

Primary: Apparent terminal half-life (t1/2) of AZD0486, Incidence of subjects with Dose-limiting toxicities (DLT), Incidence of subjects with adverse events (AEs) and/or serious adverse events (SAEs), Maximum Observed Serum Concentration of AZD0486 (Cmax)

Secondary: Anti-Lymphoma Activity by Duration of Objective Response (DOR), Anti-Lymphoma Activity by Objective Response Rate (ORR), Anti-Lymphoma Activity by Progression-Free Survival (PFS)

Body systems

Oncology