Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease
Phase 2
100
about 13 years
2–25
5 sites in DC, IL, NC +2
Why this study is shown
What this study is about
This trial is testing a new way to transplant bone marrow from an identical sibling donor into children with sickle cell disease. The goal is to reduce the side effects of this treatment while still achieving a high success rate.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Alemtuzumab, low dose total body irradiation, Sirolimus
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
alemtuzumab, sirolimus
injection (Injection), injection, intravenous
Secondary: PedsQL 4.0 Measurement model for the Pediatric Quality of Life Inventory